Characteristics of Endometrial Cells and the Factors  that Influence the Implantation Process

Manggiasih Dwiayu Larasati; ita ita

doi:10.37430/jen.v4i1.82

Characteristics of Endometrial Cells and the Factors that Influence the Implantation Process

Manggiasih Dwiayu Larasati, ita ita

Abstract

Infertility is a global health problem faced by 8 - 10% of couples in the world. It means 50 - 80 million couples have infertility problem. Knowledge about comprehensive and profound reproductive system is main asset for managing infertility. When look at various factors those contribute to women infertility, so the role of endometrium is very important. The optimal endometrial environment for receiving blastocyst is a major factor in the process of implantation and pregnancy. This study attempts to review and compare sources from research article, case report, and reviews from reputable international journals. Research by Germeyer et all (2010) shows that optimal growth and development of endometrium are factors those greatly contributes for successful implantation which is continued to pregnancy. The same thing is revealed by Neykova review (2020) which states the success implantation process is determined by the quality of the embryo, the readiness of the endometrium to accept the result of conception and interaction, and communication of molecular cells. Currently, various studies are being developed for evaluating endometrium condition through genetic improvement, the use of new biomarkers, non-invasive method even sophisticated method such as proteomic technique Endometrial Receptivity Assay (ERA) in order to solve women infertility problem.

Keywords

Keyword: Endometrium, Infertility, Implantation, Pregnancy

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References

Bibliography

S. P. Roupa Z., Polikandrioti M., W. G. Faros E., Koulouri A., and G. M., “CAUSES OF INFERTILITY IN WOMEN AT REPRODUCTIVE AGE,” Heal. Sci. J., vol. 3, no. 2, pp. 80–87, 2009.

Erwinanto, “Hubungan pertumbuhan folikel, kadar estradiol, dan ketebalan endometrium hasil induksi ovulasi dalam proses fertilisasi in vitro,” Universitas Diponegoro Semarang, 2004.

G. R. Dutta S, “A clinic-anatomical study on the common etiological faktors pertaining to primary infertility in females using some common investigative procedures,” J. Anat. Soc., vol. 56, no. 2, pp. 17–17, 2007.

A. Germeyer, M. von Wolff, J. Jauckus, T. Strowitzki, T. Sharma, and A. T. Grazul-Bilska, “Changes in cell proliferation, but not in vascularisation are characteristic for human endometrium in different reproductive failures - a pilot study,” Reprod. Biol. Endocrinol., vol. 8, pp. 1–7, 2010, doi: 10.1186/1477-7827-8-67.

A. H. Brooks AA, Johnson MR, Pawson ME, Thomas A, Phelan LK, “Endometrialthickness: Individual and mean growth profiles for different hormon replacement regimens,” Hum. Reprod., vol. 11, no. 12, pp. 2724–2731, 1996.

K. Neykova, V. Tosto, I. Giardina, V. Tsibizova, and G. Vakrilov, “Endometrial receptivity and pregnancy outcome,” J. Matern. Neonatal Med., vol. 0, no. 0, pp. 1–15, 2020, doi: 10.1080/14767058.2020.1787977.

A. M. Cohen, X. Y. Ye, T. J. Colgan, E. M. Greenblatt, and C. Chan, “Comparing endometrial receptivity array to histologic dating of the endometrium in women with a history of implantation failure,” Syst. Biol. Reprod. Med., vol. 66, no. 6, pp. 347–354, 2020, doi: 10.1080/19396368.2020.1824032.

S. Prawirohardjo, Ilmu Kandungan. Jakarta: Yayasan Bina Pustaka., 2016.

M. A. Ochoa-Bernal and A. T. Fazleabas, “Physiologic events of embryo implantation and decidualization in human and non-human primates,” Int. J. Mol. Sci., vol. 21, no. 6, 2020, doi: 10.3390/ijms21061973.

E. B. Johnson MH, Essential reproduction, 5th ed. London, United Kingdom: Blackwell Science, 2000.

H. J. Burkitt HG, Yang B, Wheather’s functional histology: A text and colour atlas. In: Tambajong J. Editor. Buku ajar & atlas wheater: Histologi functional, 3rd ed. Jakarta: Buku Kedokteran EGC, 1995.

D. B. Tortora GJ, “Essensials of anatomy and physiology,” New York: Department of economic and social affarirs, 2014.

P. ODC, “The Association Between Polycystic Ovary Syndrome and Endometrial Cancer,” University College London, 2009.

S. L. Fritz MA, “Unexplained Infertility,” in Clinical Gynecologic, Endocrinology and Infertility, USA: Lippincott Williams and Wilkins, 2011, pp. 1185–1190.

A. E. Singh M, Chaudhry P, “Bridging Endometrial Receptivity and Implantation: Network of Hormons, Cytokines, and Growth Factor,” J. Endocrinol., vol. 210, no. 1, pp. 5–14, 2011.

C. E. Gargett, R. W. S. Chan, and K. E. Schwab, “Hormone and growth factor signaling in endometrial renewal: Role of stem/progenitor cells,” Mol. Cell. Endocrinol., vol. 288, no. 1–2, pp. 22–29, 2008, doi: 10.1016/j.mce.2008.02.026.

C. G. Cooke PS, Buchanan DB, Lubahn DB, “Mechanism of estrogen action: Lesson from the estrogen receptor-α knockout mouse,” Biol. Reprod., vol. 59, no. 1, pp. 470–475, 1998.

M. C. Rendon WAC, Alvares JFC, “Blastocyst-endometrium interaction: intertwining a cytokine network,” Brazillian J. Med. Biol. Res., vol. 39, no. 1, pp. 1373–1385, 2006.

T. H. Bagot CN, Kliman HJ, “Maternal hoxa10 is required for pinopod formation in the development of mouse uterine receptivity to embryo implantation,” Dev. Dyn., vol. 222, no. 1, pp. 538 – 544, 2001.

H. ME, Endocrinology. Upper Saddle River: Prentice Hall Incorporational Inc., 2000.

J. Widayanti DT, Sugito B, PAngestiningsih TW, Kusindarta DL, “Injeksi media kultur embrio supernatant dalam uterus untuk meningkatkan angka implantasi embrio pada mencit,” J. Kedokt. Hewan, vol. 7, no. 2, pp. 155–159, 2013.

DOI: https://doi.org/10.37430/jen.v4i1.82